Eine dunklere Hautfarbe kann einen Vitamin-D-Mangel begünstigen (2024)

Vitamin D plays a crucial role in maintaining overall health and well-being. It is essential for strong bones, muscle function, and immune system support. However, certain factors can contribute to a deficiency in vitamin D, including skin pigmentation and medication use. In this article, we will explore the relationship between skin color, medication, and vitamin D deficiency, and provide insights into how to maintain optimal vitamin D levels.

Skin Color and Vitamin D Deficiency

People with darker skin tones have higher levels of melanin, a pigment that provides protection against harmful UV radiation from the sun. While this is beneficial in reducing the risk of skin cancer, it also reduces the skin's ability to produce vitamin D from sunlight. Melanin acts as a natural sunscreen, blocking a significant amount of UVB radiation necessary for vitamin D synthesis. As a result, individuals with darker skin are more prone to vitamin D deficiency, especially if they live in regions with less intense sunlight, such as northern European countries like Germany.

Medication and Vitamin D Metabolism

Certain medications can interfere with the body's ability to metabolize vitamin D, leading to a higher risk of deficiency. Some examples of these medications include:

  • Glucocorticoids like cortisone
  • Cancer drugs (cytostatics) such as docetaxel, carboplatin, and oxaliplatin
  • Breast cancer drugs from the group of antiestrogens, like tamoxifen, anastrozole, letrozole, and exemestane
  • Antiepileptic drugs like carbamazepine and phenytoin
  • HIV medications like efavirenz

If you are taking any of these medications, it is advisable to have your vitamin D levels checked at least once a year to monitor for deficiency. Medication-induced vitamin D deficiency can be managed through appropriate supplementation or dietary adjustments.

Other Risk Factors for Vitamin D Deficiency

In addition to skin color and medication use, several other factors can increase the risk of vitamin D deficiency. These include:

  • Chronic inflammatory bowel diseases
  • Malnutrition
  • Rheumatoid arthritis

Individuals with these conditions should be particularly vigilant about maintaining adequate vitamin D levels and may require regular monitoring and supplementation.

The Benefits of Vitamin D

While the relationship between vitamin D and certain diseases is still being studied, there is evidence to suggest that maintaining optimal vitamin D levels can have positive effects on bone health and muscle strength, especially in older adults. Studies have shown that older individuals with adequate vitamin D levels are less likely to experience falls, fractures, muscle weakness, mobility issues, and balance problems. They also appear to have a lower risk of premature mortality.

Vitamin D and Disease Prevention

The role of vitamin D in preventing diseases such as cancer, type 2 diabetes, dementia, and cardiovascular conditions is still unclear and requires further research. While some studies suggest that vitamin D deficiency may increase the risk of depression, preventive supplementation does not seem to reduce the risk of developing depression. It is important to note that low vitamin D levels observed in individuals with certain diseases do not necessarily imply a causal relationship between vitamin D deficiency and the disease itself. Further research is needed to establish the exact nature of the relationship between vitamin D and various health conditions.

Vitamin D During Pregnancy

Studies have shown that many pregnant women are deficient in vitamin D, even during the summer months. Adequate vitamin D levels during pregnancy are crucial for optimal fetal development. However, the use of vitamin D supplements during pregnancy is a topic of debate among experts, and there are currently no universally accepted guidelines. It is generally believed that pregnant women do not require higher doses of vitamin D than the general population. A daily intake of 20 µg (800 IU) is considered sufficient for pregnant women who are unable to produce enough vitamin D through sun exposure. However, some experts advocate for higher doses. If a pregnant woman is diagnosed with a vitamin D deficiency, a higher dosage of 37 to 50 µg (1,480 to 2,000 IU) per day may be recommended. Dosages up to 100 µg (4,000 IU) per day are considered safe for pregnant women.

Methods of Vitamin D Supplementation

If you are considering taking vitamin D supplements, it is important to consult with your healthcare provider and have your vitamin D levels tested beforehand. In some cases, increasing sun exposure may be sufficient to correct a vitamin D deficiency. However, this may not always be feasible or effective.

In cases of confirmed vitamin D deficiency, your healthcare provider may recommend vitamin D supplements in the form of tablets, capsules, oil, or drops. The dosage will depend on factors such as the severity of the deficiency and the presence of risk factors. In many cases, individuals are responsible for covering the cost of vitamin D supplements, unless they have certain medical conditions that qualify for prescription coverage.

When prescribing vitamin D, healthcare providers must consider whether the supplement is classified as a dietary supplement or a medication. Dosages up to 1,000 IU (25 µg) are generally considered dietary supplements and can be purchased without a prescription. Higher-dose vitamin D supplements are classified as medications and require a prescription. However, in certain cases, vitamin D supplements up to 1,000 IU may be prescribed, such as for individuals with osteoporosis, those undergoing long-term corticosteroid treatment, or those receiving bisphosphonate therapy.

It is worth noting that the combination of vitamin D and vitamin K supplementation is often recommended. However, the scientific evidence supporting the benefits of this combination for bone health or the prevention of calcium deposits in blood vessels is currently inconclusive. The decision to combine vitamin D and vitamin K supplementation, particularly in cases of osteoporosis, should be made in consultation with a healthcare provider.


Maintaining optimal vitamin D levels is essential for overall health and well-being. While individuals with darker skin and those taking certain medications may be at a higher risk of vitamin D deficiency, regular monitoring and appropriate supplementation can help mitigate this risk. It is important to consult with a healthcare provider to determine the most suitable supplementation strategy based on individual needs and circumstances.

Remember, this article is intended to provide general information and should not replace personalized medical advice. If you have specific concerns or questions about your vitamin D levels, consult with a healthcare professional.

Eine dunklere Hautfarbe kann einen Vitamin-D-Mangel begünstigen (2024)


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